Why Stomach Pain Persists Even When Ultrasound Results Are Normal, Explains AIIMS DoctorHealth
19 Sept 2026, 10:39 pm (55 min ago)· 0

Why Stomach Pain Persists Even When Ultrasound Results Are Normal, Explains AIIMS Doctor

Persistent or intermittent stomach pain accompanied by normal ultrasound reports is often caused by low-grade intestinal inflammation and functional abdominal pain, according to Dr. Govind Makharia of AIIMS New Delhi.

Suffering from recurring stomach discomfort that flares up for a few days, pauses, and then returns is an increasingly common complaint. Many patients seek medical advice and undergo an ultrasound examination, only to receive a completely normal report alongside a vague observation of mild intestinal swelling. This scenario leaves patients confused about why they are in pain despite clear test results and unsure about what steps to take next. Dr. Govind Makharia, Professor in the Department of Gastroenterology at the All India Institute of Medical Sciences (AIIMS), New Delhi, addressed the underlying mechanisms of this condition, the heightened sensitivity of the intestines, and how it can be resolved.

Primary Causes of Abdominal Pain and Intestinal Swelling

Abdominal swelling and discomfort stem from numerous clinical conditions. Dr. Govind Makharia explains that routine triggers of stomach pain include peptic ulcers, inflammatory bowel disease, specific gastrointestinal infections, Crohn's disease, ulcerative colitis, celiac disease, and even systemic anemia. Beyond these specific illnesses, the gut possesses an extensive network of nerves that communicate directly with the central nervous system.

Also read

When the intestines become hypersensitive, routine digestive processes, slight gas accumulation, or the normal movement of food can be perceived by the brain as acute, severe pain. In other instances, the natural rhythm of contraction and expansion in the intestinal muscles falls out of sync, triggering cramps and sharp spasms. In several individuals, diagnostic tests do not reveal any visible structural illness, a condition classified as functional abdominal pain. This demonstrates that genuine physical pain can occur without any detectable clinical disease. Consequently, evaluating the exact nature of the pain, its precise location, and the side of the abdomen where it manifests is vital. Anyone experiencing recurrent episodes of pain over multiple days should seek medical attention promptly.

Why Routine Scans Fail to Detect Low-Grade Inflammation

Patients frequently experience episodes where abdominal ache recurs unpredictably over weeks or months. Dr. Govind Makharia points out that this pattern often originates from very mild intestinal swelling that remains completely undetectable on an ultrasound scan. This swelling does not stem from a heavy bacterial infection or an overt tumor; rather, it represents what medical science refers to as microscopic swelling or low-grade inflammation.

When the nerves supplying the digestive tract remain under persistent stress, the mucosal lining of the intestines can develop low-grade irritation and inflammation. While this produces noticeable discomfort, ordinary diagnostics fail to capture it. The inflammation is so minor and microscopic that conventional ultrasounds or standard lab evaluations miss it entirely, yet it fundamentally disrupts normal intestinal mechanics. This explains why it is labeled functional abdominal pain, as the organ looks normal structurally but operates abnormally.

How Meals, Gas, and Bowel Swelling Fluctuate Discomfort

Pain arising from inflamed bowels rarely maintains a steady intensity throughout the day. According to Dr. Govind Makharia, when food boluses or trapped gas travel through the digestive canal, or when spasms grip the inflamed segment, the pain spikes abruptly. Conversely, when the gut settles into a quiescent phase, the discomfort recedes into a mild, dull ache.

Immediately following a meal, or within a window of 30 to 40 minutes, bowel motility accelerates, which can provoke sudden cramps and intense discomfort in the swollen areas. Swelling within the inner lining can narrow or slow down the digestive passage. Consequently, intestinal gas cannot pass freely and remains trapped in a single pocket, generating significant local tension and ache. Once that gas escapes, the luminal pressure drops, offering immediate physical relief. In certain presentations, the abdomen feels distended, firm, and stretched tight like a drum. Often, a severe bout of cramping triggers an urgent desire to pass stool, after which the discomfort noticeably subsides.

The Gut-Brain Axis and the Amplifying Role of Stress

Experiencing emotional or mental stress can substantially aggravate bowel pain when underlying swelling exists. Dr. Govind Makharia notes that the brain and the gut remain in continuous dialogue through millions of nerve fibers and biochemical messengers, forming what is recognized as the gut-brain axis.

During periods of mental strain, the brain releases key stress hormones, predominantly cortisol and adrenaline. These circulating hormones make the neural network in the gut excessively excitable. Under this heightened reactivity, ordinary intestinal contractions or minor gas pockets are interpreted by the brain as intense pain. Furthermore, psychological stress shifts the body into a fight-or-flight posture, disturbing the regular peristaltic contractions of the digestive muscles. Sluggish bowel transit induces constipation and traps gas, escalating wall tension in swollen intestinal segments and intensifying the underlying pain.

Distinguishing Functional Discomfort from Cancer Risks

Dr. Govind Makharia emphasizes that in very rare circumstances, persistent discomfort can be an indicator of cancer. The defining difference between routine inflammatory pain and oncological pain lies in their temporal behavior. Pain caused by standard, low-grade swelling is characteristically intermittent, appearing and disappearing over time, whereas pain caused by cancer is relentless and unyielding. Therefore, if someone suffers from identical, continuous abdominal pain that persists without relief for 15 to 20 consecutive days, an immediate comprehensive medical evaluation is imperative.

Medical Management and Dietary Prevention Strategies

Managing this condition is entirely achievable with the appropriate medical guidance. Patients should start by consulting a physician, who will review the clinical picture and ultrasound findings to diagnose the precise nature of the gastrointestinal complaint and initiate targeted medications. If standard pharmacological therapies fail to resolve the discomfort, consulting a specialist gastroenterologist is the recommended next step.

Preventing intestinal swelling centers largely on daily dietary discipline. Dr. Govind Makharia advises that safeguarding gut health begins with mindful nutrition. Incorporate fiber-rich foods into daily meals while strictly eliminating fast foods, junk items, and heavily processed meals. Opt for freshly prepared, easily digestible home-cooked food, and ensure regular intake of whole fruits, seeds, and dry fruits to maintain smooth digestive functioning.

Questions & Answers

Why does stomach pain persist even when ultrasound reports are normal?
The pain is often triggered by microscopic, low-grade intestinal inflammation that escapes ultrasound detection but makes gut nerves hypersensitive.
What is functional abdominal pain?
It is a condition where a patient experiences genuine abdominal pain caused by nerve sensitivity and altered gut function without visible clinical disease.
Why does abdominal pain spike 30 to 40 minutes after eating?
Digestive motility increases after meals, provoking spasms and trapping gas across swollen or sluggish intestinal segments.
How does mental stress aggravate abdominal discomfort?
Stress hormones such as cortisol sensitize gut nerves through the gut-brain axis and disrupt muscular contractions, aggravating pain and gas.
When is it critical to seek immediate medical consultation?
If identical, unyielding stomach pain persists continuously for 15 to 20 days, an immediate evaluation is needed to rule out rare risks like cancer.
What dietary measures help prevent intestinal inflammation?
Eating home-cooked digestible food rich in dietary fiber, fruits, seeds, and nuts while avoiding fast food and processed meals protects the gut.

Comments 0

No comments yet — be the first.

Citizen journalism

Become a TrendKia journalist

Voice of the people

Share news, photos and videos from your area with TrendKia and let your voice reach the nation. Every citizen a journalist.

Join now
CH 01 LIVE
TrendKia TV ON AIR
Chamar no WhatsApp